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- Anti-Mouse IFNgamma [H22] In Vivo Antibody - Ultra Low Endotoxin (IVMB0034)
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Product Description
Anti-Mouse IFNγ [H22] In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse IFN-γ [H22] In Vivo Antibody - Ultra-Low Endotoxin from Assay Genie, a highly specific monoclonal antibody optimized for in vivo applications. This antibody targets the interferon-gamma (IFN-γ) protein, a crucial cytokine in immune response modulation, making it an excellent choice for research in immunology and related fields. With a rat IgG1 isotype, it ensures high purity and ultra-low endotoxin levels (<1.0 EU/mg), suitable for a variety of assays including ELISA, flow cytometry, and functional experiments. Formulated in phosphate-buffered saline, this antibody is designed for stability and efficacy in your research applications.
Available in multiple sizes, it is an essential tool for enhancing the accuracy and reliability of your immunological studies. IFN-γ is a powerful cytokine produced primarily by T cells and natural killer (NK) cells. It plays a pivotal role in innate and adaptive immunity, including the activation of macrophages, induction of antigen processing and presentation, and modulation of adaptive immune responses. Elevate your immune response research with the dependable and versatile Anti-Mouse IFN-γ [H22] In Vivo Antibody from Assay Genie.
| Product Name: | Anti-Mouse IFNgamma [H22] In Vivo Antibody - Ultra Low Endotoxin |
| Product Code: | IVMB0034 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | H22 |
| Protein: | IFN-gamma |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFNγ |
| Isotype: | Armenian Hamster IgG |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse IFN-gamma (>98%) |
| Applications: | ELISA, IF, IP, N, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | ELISA, IF, IP, N, WB |
| Recommended Usage: | WB The suggested concentration for this clone H22 antibody for use in western blotting is 0.5 µg/ml. |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Specificity: | Armenian Hamster Anti-Mouse Interferon Gamma (IFN-gamma) (Clone H22) recognizes an epitope on Mouse IFN-gamma. This antibody was also pathogen tested and third-party certified by IDEXX BioReseach to meet the lowest mycoplasma specification and free of any viral pathogens of concern. |
| Immunogen: | Purified Recombinant Mouse IFN-gamma (>98%) |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | >0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.3 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.4 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.5
| Datasheet: | View |
| Protein: | IFN-gamma |
| Ligand/Receptor: | IFN-γRα (CDw119) dimerized with IFN-γRβ (AF-1) |
| Research Area: | Immunology |
| Armenian Hamster IgG Isotype Control | |
|---|---|
| Clone | PIP |
| Isotype | Armenian Hamster IgG1 |
| Endotoxin Level | Ultra Low Endotoxin |
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