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- Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin (IVMB0167)
![Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin](https://cdn11.bigcommerce.com/s-h68l9z2lnx/products/214502/images/569388/anti-mouse-icam-1-cd54-be29g1-in-vivo-antibody-ultra-low-endotoxin__83512.1770916022.1280.1280.jpg?c=2 "Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin")
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Product Description
Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse ICAM-1 [BE29G1] In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the ICAM-1 (CD54) protein, which plays a critical role in leukocyte endothelial transmigration, making it ideal for research in immunology, inflammatory responses, and related fields. With a rat IgG2a kappa isotype, it ensures high purity and ultra-low endotoxin levels (<0.01 EU/μg), perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy.
Enhance your research with this reliable and versatile antibody. ICAM-1 is a transmembrane glycoprotein expressed on endothelial cells and cells of the immune system. It is essential in the immune system’s inflammatory response by facilitating leukocyte adhesion and transmigration across the endothelium. This makes the Anti-Mouse ICAM-1 [BE29G1] In Vivo Antibody a valuable tool for investigating inflammation, immune cell interactions, and disease mechanisms.
| Product Name: | Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin |
| Product Code: | IVMB0167 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | BE29G1 |
| Protein: | ICAM-1 |
| Product Type: | Monoclonal Antibody |
| Synonyms: | BB2, CD54, P3.58 |
| Isotype: | Rat IgG2a |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse ICAM-1 (>98%) |
| Applications: | B, IP, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | B, IP, WB |
| Recommended Usage: | WB |
| Reactivity: | Mouse |
| Host Species: | Rat |
| Specificity: | Clone BE29G1 recognizes mouse ICAM-1. |
| Antigen Distribution: | CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. |
| Immunogen: | Purified Recombinant Mouse ICAM-1 (>98%) |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
ICAM-1 is a 55 kDa glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. ICAM-1 is known to be an adhesion and viral entry molecule, and its long suspected involevement in signal transduction is being elucidated. The signal-transducing functions of ICAM-1 appear to be mainly associated with proinflammatory pathways. Furthermore, ICAM-1 signaling appears to act as a beacon for inflammatory immune cells such as macrophages and granulocytes bringing about inflammation via lymphocyte trafficking. ICAM-1 is essential for the transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. ICAM-1 is the receptor for rhinoviruses (the cause of most common colds) and malaria, and plays an inflammatory role in ocular allergies.
| Datasheet: | View |
| Protein: | ICAM-1 |
| Research Area: | Cell Adhesion, Cell Biology, Neuroscience, Neuroscience Cell Markers |
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